Background:Intermediate uveitis (IU), pars planitis, chronic cyclitis, peripheral uveitis, vitritis, cyclochorioretinitis, chronic posterior cyclitis and peripheral uveoretinitis are the names that have been used to describe inflammation in the anterior vitreous, ciliary body and the peripheral retina.Interleukin-8 (IL-8) is a chemoattractant cytokine produced by a variety of tissue and blood cells.Hence; the present study was conducted for evaluating IL-8 levels in intermediate Uveitis patients. Materials & methods:A total of 50 patients with presence of intermediate uveitis were enrolled. Another set of 50 subjects of healthy controls were enrolled as control group. Complete demographic and clinical details of all the patients was obtained. Blood samples were obtained and serum IL-8 levels were evaluated using auto-analyzer. All the results were recorded in Microsoft excel sheet and was subjected to statistical analysis using SPSS software. Results:Mean age of the patients of the intermediate uveitis group and control group was 43.1 years and 40.8 years respectively. Mean IL-8 levels among patients of the intermediate uveitis group and control group were 723.8 pg/ml and 208.7 pg/ml respectively. Significant results were obtained while comparing mean IL-8 levels among intermediate uveitis group and control group. Conclusion:IL-8 levels are significantly altered in intermediate uveitis patients.