Etiologically it may be due to painful gut contractions caused by allergy to cow’s milk, hyper peristalsis due to increased motilin transient lactase deficiency or motility dysfunction, neutrophilicinfiltration, altered intestinal microflora, increased intra-abdominal gas, visceral pain, increased faecalCalpotectin levels as a possible role for gut inflammation. Informed consent was taken for those who fulfilled Modified Wessel’s criteria of crying for more than 3 hours a day for at least 3 days in a week. Babies were randomized into 2 groups according to computer generated block randomization by an independent statistician. The components of PQAL score namely physical, emotional, functional and cognitive functioning were similar in both the groups (p>0.05). Also, components of family summary score namely daily activities and family relationships scores were similar in both the groups (p>0.05). The total PQAL and Family summary scores were similar in both groups at the start of the study. PQAL score was significantly higher in group A compared to group B at the end of study (p<0.05).