Background: The exact cause of appendicitis is often unknown, but it can occur when the appendix becomes blocked, typically by fecal matter, a foreign body, or, in some cases, a tumor. The present study was conducted to assess RIPASA score in patients with acute appendicitis. Materials & Methods: 70 patients of acute pancreatitis of both genders were enrolled. The eight-variable RIPASA scoring system was used to evaluate the patients. Depending on the score, patients were classified into four groups: 5, 5-7, 7.5-11.5, and >12. Results: Out of 72 patients males were 42 and females were 30.RIPASA score in male and female was <5 seen in 12% and 13%, 5-7 in 8% and 17%, 7.5-11.5 in 65% and 40% and >12 in 35% and 30% respectively. The difference was significant (P< 0.05). Conclusion: For the diagnosis of acute appendicitis, the RIPASA score is a better, simpler, safer, and non-invasive diagnostic technique.