Background:Urticaria is described as erythematous, cutaneous swellings of short duration, occurring as a result of vasodilation and dermal oedema. It consists of wheal and flare reaction which is characterized by localised intra cutaneous oedema. Urticaria is a distressing dermatologic condition which require prolong treatment and proper counselling of patient. Aims & Objectives: 1. To study the clinico-epidemiological profile of patients presenting with chronic idiopathic urticaria. 2. To study and investigate serum ferritin and serum vitamin D levels in patients with chronic idiopathic urticaria. Materials and Methods:A hospital based descriptive study was conducted among 80 subjects at a tertiary care teaching centre for a period of one and half year. The collected data was analysed using SPSS version 21. Results:The mean age of the study subjects was 47.81 years, with 28.75% of them in >61 years of age followed by the age group of 41-50 years. 52.5% of total study subjects were males and 47.5% were females, with the male to female ratio of 1.1:1. We noted that out of 80 patients, Vitamin D deficiency was more common in chronic urticaria patients 81.25% (n=65) followed by Iron deficiency 56.25% (n=45). Conclusion:In this study out of 80 chronic urticaria patients; 36 (45%) patients had both vitamin D and Iron deficiency. 29 (39%) patients had vitamin D and 9 (12%) patients had Iron deficiency respectively