Endotracheal intubation is the definitive technique to secure the airway. It is the reliable method of securing the airway and is considered the standard of care for protecting the airway from aspiration.Endotracheal intubation requires expertise and is invasive requiring muscle relaxation. LMA Supremeplacement is quick and simple withnil or minimal use of neuromuscular inhibition and less postoperative morbidity.Appropriate mouth opening and little to no airway reflexes, such as choking, coughing, or laryngospasm, are required for a smooth and effective insertion. Although induction drugs like propofol and etomidate are known to dull laryngeal reflexes, patient movement, coughing, and gagging frequently make the situation uncomfortable along with erratic hemodynamic changes.In the current study, we compared ketamine-propofol mixture (ketofol) with etomidate - propofol (etofol) to assess the Supreme LMA insertion circumstances and hemodynamic changes in laproscopic tubectomies.The present study was a prospective, randomized, double blinded study carried out in a tertiary care hospital in Karnataka. Women undergoing elective laparoscopic tubectomies during the study period (Jan 2018 to Dec 2018) were considered for the present study. The study subjects were allocated to two different groups using software generated random numbers. Assessment of lma insertion among study subjects revealed that majority of patients in both the study groups had mouth opening after induction (84% in etofol group and 88% in ketofol group) (table 2). There was statistically no significant difference in the lma supreme insertion conditions among both the study groups.