Background: Reporting for ADRs (adverse drug reactions) forms the basic structural unit in the pharmacovigilance program. It has been reported that undergraduate medical students in India have underreported pharmacovigilance. Aim: The present study, using a questionnaire, aimed to assess the practice, attitude, and knowledge of pharmacovigilance in Indian undergraduate medical students. Methods: The present study utilized a cross-sectional questionnaire-based design and the questionnaire used in the study comprised 21 questions for evaluation of KAP (knowledge, attitude, and practice of undergraduate students concerning pharmacovigilance. Results: The study results showed that mean KAP scores for 2nd years, prefinal, and final-year students were 4.71, 5.61, and 4.74 respectively for knowledge, 4.24, 4.93, and 4.51 for attitude, and 1.64, 1.53, and 1.26 for practice. Also, a significant difference was seen in an intergroup comparison of mean scores in three groups for attitude and knowledge. However, a non-significant difference was seen for practice. Students showed a better attitude, but poor practice and knowledge of pharmacovigilance. Conclusion: The present study concludes that undergraduate Indian medical students lack adequate skill and knowledge for reporting adverse drug reactions, however, they have a positive attitude concerning the pharmacovigilance program. Integration of undergraduate curriculum with pharmacovigilance can help in the improvement of reporting and monitoring of ADRs.