Background: Radial nerve palsy (RNP) is a frequent complication of humerus fractures, with a significant impact on upper limb function and patient quality of life. This study aims to assess the factors influencing the incidence and recovery of RNP in humeral fractures.Material and Methods: A total of 100 patients diagnosed with humerus fractures were analyzed for RNP occurrence, potential influencing factors, and recovery outcomes. Data on fracture type, location, mechanism of injury, treatment method, and rehabilitation approaches were collected.Results: The study found that midshaft fractures and high-energy trauma were strongly associated with RNP (p = 0.03). The incidence of RNP among the study population was 25%. Among these, 72% of patients showed recovery within six months (p = 0.02), with an overall recovery rate of 85% within one year (p = 0.01). Non-surgical management yielded promising results in cases where nerve continuity was preserved, while surgical exploration was necessary for 30% of affected patients (p = 0.04).Conclusion: The study highlights the importance of early diagnosis and appropriate intervention in improving functional outcomes. While most patients recover spontaneously, structured rehabilitation programs further enhance recovery. The findings underscore the need for tailored management strategies based on fracture characteristics and patient factors..