Introduction: The most commonly seen endocrinopathy that have been most commonly crossed is polycystic ovarian syndrome. It affects almost 6 – 10% of women in their reproductive age group. Hence this study discusses the prevalence of anxiety and depression in polycystic ovarian syndrome among patients attending the tertiary care center in Central India. Materials and Methodology: In this study, there were 100 patients of PCOS reporting from the Department of Obstetrics and Gynecology, Peoples College of Medical Sciences and Research Centre, Bhopal MP, India. This study included those patients who were attending the outpatient and who had confirmed diagnosis of PCOS earlier. A semi-structured questionnaire was used to gather information about socioeconomic status and clinical symptoms. Clinical symptoms assessment included menstrual history; reproductive history; BMI; body hair, which were assessed using Ferriman–Gallwey scoring system acne, which were assessed on global acne grading system (GAGS). Data were expressed as proportions. Results: In this study of 100 women of PCOS mean age (SD) was 25.42 (3.68) and most of women had education level of 10 – 12 years. Interval between menstruation days was variable in majority and more than two-thirds had never been pregnant. Sociodemographic and clinical characteristics are shown in following Table. Conclusion: Prompt pharmacological treatment followed by psychotherapeutics and psychosocial support should also be considered while treating such women with PCOS.