Introduction: Dry eye disease (DED) is a common ocular condition characterized by insufficient tear production or poor tear quality, leading to discomfort, irritation, and visual disturbances. Objectives: The main objective of the study is to find the efficacy of 2% hydroxypropyl methylcellulose and bandage contact lens for the management of dry eye disease after cataract surgery. Material and methods: This retrospective study was conducted and the Data was collected from 85 dry eye patients. Baseline demographic and clinical characteristics of the patients enrolled in the study were collected at the initial visit. These included age, gender, medical history, and previous ocular surgeries. Following randomization, patients were assigned to either the 2% hydroxypropyl methylcellulose (HPMC) eye drops group or the bandage contact lenses group.Results: Data were collected from 85 patients from both genders. Mean age of the patients was 65.4 ± 7.8 years. There were 38 (45%) male and 47 (55%) female patients. The majority of participants had no significant medical history, with 78% reporting no underlying health conditions. Among those with medical history, hypertension was the most prevalent at 14%, followed by diabetes at 8%, and other conditions accounted for 6%. The adherence rates were high in both treatment groups, with participants in the 2% hydroxypropyl methylcellulose (HPMC) eye drops group exhibiting an adherence rate of 97.5% ± 2.1%, and those in the bandage contact lenses group showing a slightly lower adherence rate of 96.8% ± 2.5%. Conclusion: It is concluded that both 2% hydroxypropyl methylcellulose (HPMC) eye drops and bandage contact lenses demonstrate efficacy in managing dry eye disease following cataract surgery. The significant improvements observed in dry eye symptoms, tear film stability, and corneal epithelial healing support the use of both interventions in clinical practice.