Original Articles
Evaluation of reduction in tumor volume on pre brachytherapy MRI Scan in patients of Carcinoma cervix | |
K Vijay Kumar, Roja Kiran Gajula, Jagadeesh Pavuluru, Srinivas D | |
Background: Cervical cancer is the fourth most common malignancy diagnosed in women worldwide and second most common malignant tumor in women in India. Hence; the present study was conducted for evaluating reduction in tumor volume on pre brachytherapy MRI Scan in patients of Carcinoma cervix. Materials & methods: A total of 50 patients with carcinoma of cervix were enrolled.Inclusion criteria included patients receiving curative treatment with external beam radiotherapy along with concurrent chemotherapy followed by intracavitary or interstitial radiotherapy. Pre-and post EBRT imaging information was collected and tumor reduction volume reduction rate and residual tumor volume was calculated. Results: Data of a total of 50 patients was analysed during the study period. Mean age of the patients was 49.5 years. Progressive diseases were encountered in 2 percent of the patients.Mean pre-external beam radiotherapy volume (V1) and mean post-external beam radiotherapy volume (V2) was found to be 45.3 cc and 8.7 cc respectively. Overall Tumor volume reduction rate was found to be 80.79 %. Overall survival and locoregional failure free survival was found to be 68.13 months and 67.81 months respectively. Conclusion: Pre-brachytherapy MRI may assist in identifying appropriate candidates for brachytherapy and ensuring the administration of the prescribed doses to the tumor. |
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