Introduction: Sexual dimorphism in the femur refers to the observable differences between male and female femurs in terms of size, shape, and structural characteristics. Generally, male femurs are larger and more robust than their female counterparts, exhibiting greater overall length, width, and thickness, which is attributed to greater muscle mass and body size in males. Materials and methods: The present study focused on 50 adult right femora, consisting of 25 from males and 25 from females, collected from various medical colleges' Anatomy departments. Specific measurements were taken to assess the morphological characteristics of the femur. This included weight, measured using an electronic weighing machine with a sensitivity of 0.1 grams; maximum length, calculated as the straight distance from the highest point of the femoral head to the deepest point on the medial condyle using an osteometric board; maximum head diameter, measured with a Vernier caliper; and head circumference, determined at the border of the articular surface using a flexible measuring tape. Additionally, midshaft measurements were taken, including the anteroposterior diameter at the midpoint of the diaphysis at the highest elevation of the linea aspera, the transverse diameter taken perpendicular to the anteroposterior measurement, and midshaft circumference assessed with a flexible measuring tape. Lastly, the distal epiphyseal breadth was measured as the distance between the most prominent points on the epicondyles with a Vernier caliper. These measurements aim to provide detailed data on femoral morphology and contribute to the understanding of sexual dimorphism, with implications for clinical applications and orthopedic research. Data analysis was done using SSPS software. Results: The study found that male femurs had significantly greater dimensions than female femurs across all measured parameters, including maximum length, mid-shaft diameter, condylar width, and head circumference. Conclusion: This study confirms significant sexual dimorphism in femoral dimensions, with males showing larger and more robust measurements than females. While valuable, further research with larger, diverse samples is needed to enhance forensic and orthopaedic applications.