Background: Upper Tract Urothelial Carcinoma (UTUC) is a rare tumor originating anywhere, from the renal calyces to the ureteric orifices. Methods: We intended to observe the demographical and clinico-pathological features of UTUC patients in our hospital. Results: 20 patients of UTUC with median age of 44.7±9.25 years , male to female ratio of 5.7 were studied for a follow up period of 6 months. Majority of the patients 13(65.0%) presented with painless gross hematuria. All UTUC patients 20(100%) had pre-operative hydronephrosis, 13(65%) were smokers. The most common comorbidity in our patients was hypertension. 12(60%) and 7(35%) patients were diabetics. Open nephroureterectomy was done in all patients. The average maximum size of UTUC was 4.1cm range (2-10cm). Most of the patients 10(50%) had stage II disease followed by stage III & IV in 7(35.0%) and 3(5.0%) patients respectively. There was a preponderance of papillary morphology 12(60.0%) in our patients. 95.0% of the patients had high grade tumors. Conclusion: In addition to having an excellent back up from radiology, pathology and medical oncology,it is important to know the epidemiology, natural history, genetics and etiological risk factors for this malignancy so thatnew modalities may be explored to reduce diagnostic challenges and improve patient management