Introduction: Acute pancreatitis is a potentially fatal disease. Severe acute pancreatitis can result in complications like multiple organ failure and even death. The study was conducted to know the usefulness of CRP levels as a gauge for acute pancreatitis severity. Aim: To study relation of CRP level as predictor severity of acute pancreatitis. Patient & methods: A size of 60 patients meeting inclusion criteria was taken for study. C reactive protein was done at the time of admission by standard method and was compared with modified CT severity index. Results: Patients with higher levels of CRP had higher modified CT severity index. The association was statistically significant (P<0.05). Conclusion: CRP being simple, cheaper and easily available can be used as a tool in early detection of severity of acute pancreatitis and further treatment planning in these patients.