Background: Tuberculosis (TB) is an ancient human disease caused by Mycobacterium tuberculosis which mainly affects the lungs, making pulmonary disease the most common presentation. The present study was planned and carried to determine the pattern of HRCT findings in active and inactive Pulmonary Tuberculosis and to evaluate their possible use in predicting disease activities. Material & methods: The present study was conducted among 103 patients who were clinically diagnosed with active pulmonary tuberculosis and inactive disease and was evaluated using high resolution computed tomographic spectrum (HRCT) chest scanning. Data so obtained was entered in Microsoft excel and was managed in SPSS version 16. Results: It was showing statistically significant relationship (P<0.01) of Centri - lobular nodule and/ or branching linear structure with active and inactive cases of pulmonary Tuberculosis, Tree - in - bud appearance findings with active and inactive cases of Pulmonary Tuberculosis and macro nodule with active and inactive cases of pulmonary tuberculosis. It was showing statistically significant relationship (P<0.01) of cavity with active and inactive cases of pulmonary tuberculosis, consolidation with active and inactive cases of pulmonary tuberculosis. It was showing statistically non-significant relationship (P=0.097) of collapse/atelectasis with active and inactive cases of pulmonary tuberculosis. There was a statistically significant relationship (P=0.03) of bronchial wall thickening with active and inactive cases of pulmonary tuberculosis. and non-significant relationship (P=0.554) of Ground glass opacity with active and inactive cases of pulmonary tuberculosis. There was a statistically non-significant relationship(P=0.827) of bronchiectasis with active and inactive cases of pulmonary tuberculosis and statistically significant relationship (P<0.01) of emphysema with active and inactive cases of pulmonary tuberculosis, statistically non-significant relationship (P=0.07) of bronchovascular distortion with active and inactive cases of Pulmonary Tuberculosis. There was statistically significant relationship (P<0.01) of fibrotic changes with active and inactive cases of pulmonary tuberculosis, statistically significant relationship (P=0.008) of calcified mediastinal lymph node enlargement with active and inactive cases of pulmonary tuberculosis and statistically non-significant relationship (P=0.485) of parenchymal calcification with active and inactive cases of pulmonary tuberculosis and statistically non-significant relationship (P=0.315) of pleural thickening or retraction with active and inactive cases of pulmonary tuberculosis. It was showing statistically significant relationship (P<0.01) of lymphadenopathy (>10mm) with active and inactive cases of pulmonary tuberculosis, statistically non-significant relationship (P=0.291) of pleural effusion with active and inactive cases of pulmonary tuberculosis and statistically non-significant relationship (P=0.36) of Miliary Nodules with active and inactive cases of pulmonary tuberculosis. Conclusion: The present study concluded that although chest radiography foremost imaging technique because of easy availability and cost effective in the evaluation of pulmonary TB, HRCT can be useful in certain circumstances and can provide important information in the diagnosis and management of the disease.