Original Articles
To Study the Link Between Metabolic Syndrome and Bronchial Asthma | |
Naila Ambrin, Imrana Masood, Shadab Ahmed, Sadaf Shadan | |
Abstract: Bronchial Asthma and Metabolic Syndrome are major public health problems that have increased worldwide. Asthma is a chronic inflammatory disorder characterized by reversible air flow limitation and hyper responsiveness of airway site n A compasses multiple phenotypes. Metabolic syndrome is comprised of hypertension, dyslipidemia obesity and insulin resistance leading to type two Diabetes Mellitus. Bronchial Asthma is a major cause of morbidity across the globe, there are several guidelines for the management of asthma including GINA, BTS but several factors still need to be addressed and asthma continues to be a major public health problem. The underlying mechanisms of interaction between bronchial asthma and metabolic syndrome need further research so as to reduce global asthma burden and to reduce its exacerbations. MS is a condition of systemic inflammation that could partially have an influence on asthma on set severity as well as its control. Materials and Methods: This Cross sectional study enrolled 350 patients of BA on the basis of their clinical diagnosis, supported by spirometry, blood pressure serum lipid profile, fasting and post parandial blood sugar level for diagnosing metabolic syndrome. This was analyzed to find correlation, characteristics and the determinants of Metabolic Syndrome were identified significant association was determined using latest version of SPSS statistical analysis, student t test and other relevant stats. Results: Our Study showed significant correlation between BA and MS as shown by p value and highlighted the importance of screening asthmatics for Metabolic syndrome and to include this in routine workup plan. |
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