Introduction: The quantum molecular resonance (QMR) device is an innovative energy-based devices (EBDs) that has been safely and effectively applied in otolaryngology-head and neck surgeries. The present study was undertaken to compare intraoperative parameters of tonsillectomy performed using molecular resonance generator technique and conventional method. Materials and Methods: The present study was conducted in the Department of Otorhinolaryngology among 80 Patients attending ENT OPD who were randomly selected for tonsillectomy by Molecular resonance generator and Conventional method. Time needed to perform surgery on each patient, blood loss during surgery, post operative pain, postoperative hemorrhage and extent of wound healing after surgery was recorded. Results:The majority of patients were in the age group 7 to 10(46.25%) years, The next majority age group was 4 to 6 years (26.25%). It took an average of 11 minutes 3 seconds more mean duration to perform conventional technique as compared to MRG procedure and this difference was statistical significance ( p value <0.0001). The amount of intra operative blood loss on an average in MRG method is approximately 16 ml and the amount of intra operative blood loss in conventional is 44 ml which was statistically significant p -value (< 0.001). Conclusion: Molecular resonance generator method tonsillectomy is relatively easy technique to perform providing a near bloodless field and minimal surrounding tissue damage. The operative time required to perform molecular resonance generator method tonsillectomy was less than the conventional method.The intra operative blood loss was significantly less on the molecular resonance generator method than on the dissection method.