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Volume 7 Issue 1 ( January-June) 2018

Original Articles

Diagnostic accuracy of CT in pediatric hepatoblastoma taking histopathology as gold standard
Agrawal Yojit Kailash

Introduction: Hepatoblastoma is the most common primary malignant liver tumor in children, accounting for approximately 80% of cases. Objectives: The main objective of the study id to find the diagnostic accuracy of CT in pediatric hepatoblastoma taking histopathology as gold standard. Materials and Methods: This is a cross-sectional study aimed at evaluating the diagnostic accuracy of CT imaging in pediatric patients with suspected or confirmed hepatoblastoma, using histopathological examination as the reference standard. Results: Data were collected from 76 patients with an age range of 0.5 to 12 years, with a median age of 3.8 years. The gender distribution showed 55% males and 45% females. The primary symptom among patients was abdominal swelling or pain, with most cases presenting with abdominal swelling. Additionally, elevated alpha-fetoprotein (AFP) levels were observed in 82% of the patients, aligning with common hepatoblastoma markers. The diagnostic performance of CT imaging for detecting pediatric hepatoblastoma showed strong sensitivity at 95% and a positive predictive value (PPV) of 92%, indicating high reliability in identifying true cases. Specificity was 67%, with a negative predictive value (NPV) of 77%, reflecting some limitations in accurately ruling out non-hepatoblastoma cases. Conclusion: It is concluded that CT imaging demonstrates high sensitivity and diagnostic value in detecting pediatric hepatoblastoma, particularly in assessing tumor size and vascular involvement.

 
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