Introduction: Female infertility is a complex condition, and it can arise from various causes, including hormonal imbalances, ovulatory dysfunction, and structural abnormalities in the reproductive organs. Objective: To evaluate the diagnostic value in terms of hysterosalpingography in the detection and evaluation of female infertility. Material and Method: This descriptive, cross-sectional study was conducted and data were collected through non-probability consecutive sampling technique.Data collection began following ethical approval from the hospital's ethical committee. Each patient underwent preliminary examinations, including a transvaginal ultrasound, followed by an HSG procedure. Results: Data were collected from 331 patients with mean age of 29.5± 5.8 years, predominantly within the 20–29 age group (47.7%). The average duration of infertility was 3.4 years, with primary infertility observed in 63.4% of patients and secondary infertility in 36.6%. The mean BMI was 26.3 kg/m², reflecting a generally healthy weight range. Baseline ultrasound findings showed that 75.5% of patients had normal results, while 24.5% had abnormal findings. Among patients with less than 2 years of infertility, bilateral tubal occlusion and uterine abnormalities were present in 8.4% and 2.8% of cases, respectively. These rates increased to 13.7% and 5.4% for those with 2–5 years of infertility, and further to 18.9% and 8.7% among those with infertility lasting more than 5 years. Conclusion: It is concluded that hysterosalpingography (HSG) is an effective diagnostic tool for detecting tubal and uterine abnormalities associated with female infertility.