Background: Breast feeding is known for its several benefits for both the infants and mothers. Despite strong evidences in support of breast feeding its practices has remained low among lactating mothers. The objective of the present study was to examine the knowledge, attitude, awareness and practice of exclusive breast feeding among post natal mothers at a tertiary hospital.Methods:A cross sectional study was conducted among randomly selected 105 postnatal mothers at postnatal and postoperative ward on day 2 at a tertiary care center. Face-to-face interview using a structured questionnaire was used to collect the data.Results: Among 105 study participants, majority 45 women (42.86%) were between 26-30 years, 44 women (41.91%) had secondary education, 54 women (51.43%) were multiparous, 81 women (77.14%) had vaginal delivery. Knowledge regarding breast feeding among study participants were poor, as majority of women 58 (55.24%) did not give breast milk immediately within one hour, 83 women (79.05%) thought that Pre-lacteal feed is not harmful, 71 women (67.62%) thought that discarding first milk or colostrum is important and 58 women (55.24%) thought that starting complementary foods before 6 months is important. Attitude regarding breastfeeding among study participants was quite good, as majority 83 women (79.05%) thought that breastfed babies were healthier than non breastfed babies, 96 women (91.43%) thought that breastfeeding was more convenient than formula feeding, 85 women (80.95%) thought that breast feeding increases mother-infant bonding, 79 women ( 75.24%) and 87 women (82.6%) thought that both women and infants will not have any problems when exclusive breast feeding is done and 86 women ( 81.90%) thought that exclusive breast feeding is better than artificial feeding. Awareness and practice regarding breastfeeding among study participants was quite good, as majority of women 53 (50.47%) initiated breast feeding within 1hour, 59 women (56.19%) did not discard the first milk or colostrum, 62 women (59.05%) did not give any pre- lacteal feed, 89 women (84.76%) did night feeding as a part of routine.Conclusion:Even though our findings show that attitude, awareness and practice was quite good among the study participants, knowledge regarding breastfeeding was poor and overall knowledge, attitude, awareness and practice need to be enlightened among mothers who are prenatal, antenatal and postnatal by educating them.