Background: Etiological profile of gastrointestinal (GI) bleeding varies from benign conditions to life-threatening disorders, affecting either the upper or lower gastrointestinal tract with varied clinical presentations. Aims and objectives: This study was aimed to investigate the clinical profile and etiological spectrum of both upper and lower GI bleeding in children. Material and Methods: This was a cross-sectional study carried over a period of 18 months at a tertiary care from central India. Consecutive children from 1 month to 18 years of age presenting with history of upper or lower gastrointestinal bleeding were included. Data on demographics parameters, clinical presentations and aetiology were recorded in a data collection sheet. Results: Of 54 children included in our study, 31 (57%) were male with a mean age of 11 (SD-2.5) years at presentation. Majority had upper GI bleeding (n=39; 72%) while 13 (24%) had lower GI bleeding and 2 (4%) combined presentation. Most of the children had small volume (n=32; 59%) and painless bleeding (n=38; 70%). Anemia was found in all and blood transfusion was required in 21 (39%) children. Splenomegaly was present in 38 (70%) of children. The most common cause of upper GI bleeding was esophagealvarices, [23, 59%] followed by gastritis [6; 15.4%]. Most common etiology of lower GI bleeding was single polyp, [n=3; 23%]. Conclusion: Upper GI bleeding was far common than lower GI bleeding with majorityhaving small volume, painless GI bleeding. Variceal bleeding and polpys were the commonest causes of upper and lower GI bleeding respectively.