Background: Non-venereal genital dermatoses in adult males encompass a diverse spectrum of inflammatory, infectious, autoimmune, and neoplastic conditions affecting the genital region. These disorders can present with a variety of clinical manifestations, including rash, erosions, ulcerations, papules, nodules, and plaques, often leading to discomfort, pain, and psychological distress. Material and Methods: This study was conducted in the Department of Dermatology on 100 adult male patients over the age of 18 years, presenting with non-venereal dermatoses of the external genitalia. Patients with any venereal disease were excluded. A detailed history was taken, and clinical examinations were performed, including tests like Gram’s stain, KOH mount, Tzanck smear, patch test, and skin biopsy where necessary. Data were recorded and analyzed using SPSS version 22.0. Results: The majority of patients were younger adults, with 25% in the 21-30 age group. Most patients (60%) had lesions confined to the genital region. Inflammatory conditions were the most common (38%), followed by infections (28%) and benign lesions (20%). Pre-malignant and malignant conditions were rare, comprising only 4% of cases. Systemic involvement was seen in 20% of patients, and orogenital lesions were present in 10% of patients. Conclusion: Non-venereal genital dermatoses are most common in younger males and are predominantly inflammatory. While the majority of cases are localized to the genital area, a significant number involve systemic manifestations. Vigilant clinical evaluation and timely diagnosis are crucial to effective management and early detection of pre-malignant or malignant conditions.