Background: Anterior segment ischemia will lead to neovascularization of the iris and the anterior chamber angle and mainly caused by retinal ischemia and hypoxia due to an ocular ischemic diseases as central (CRVO) or branch retinal vein occlusion (BRVO), proliferative diabetic retinopathy (PDR) and other causes include sickle cell retinopathy, retinal embolic diseases, chronic retinal detachment and inflammatory conditions as uveitis and vasculitis.Material and Methods: A prospective observational study was conducted in the Department of Ophthalmology, involving 130 eyes from 110 patients diagnosed with NVG. Detailed ocular examinations were performed, including visual acuity, slit-lamp bio-microscopy, IOP measurement using Goldmannapplanation tonometry, and gonioscopy to assess the angle status. Neovascularization of the iris (NVI) and associated complications, such as hyphema, were noted. Fundus examination and, when necessary, B-scan ultrasonography were used to visualize the retina in cases of corneal opacity. Results: Of the 110 patients, 70 were male (63.64%) and 40 were female (36.36%). Most patients were between 40-50 years of age (27.27%), followed by those in the 30-40 and over 50-year age groups (22.73% each). The stages of NVG were classified into angle closure stage (38.46%), open angle stage (30.77%), and rubeosisiridis stage (30.77%). Diabetic retinopathy was the leading cause of NVG, accounting for 38.46% of cases, followed by retinal detachment (15.38%) and vein occlusion (15.38%). The mean IOP was 30.15 mm Hg (SD 5.12) in the angle closure stage, 24.85 mm Hg (SD 4.58) in rubeosisiridis, and 18.30 mm Hg (SD 3.45) in the open angle stage.Conclusion: NVG predominantly affects middle-aged to elderly individuals, with diabetic retinopathy being the leading cause. As NVG progresses, intraocular pressure increases, with the highest levels observed in the angle closure stage. Early diagnosis and intervention are crucial to managing NVG and preventing severe visual impairment, particularly in diabetic patients.