Background: Acute pancreatitis (AP) represents a prevalent gastrointestinal condition leading to hospitalization. The present study was conducted to analyze prognostic value of computed tomography in the early evaluation of patients presenting with acute pancreatitis. Materials &Methods: A total of 100 patients who were diagnosed with acute pancreatitis by clinical and analytic criteria were enrolled. All had undergone unenhanced and contrast-enhanced helical CT within the first 24 hr after hospitalization; therefore, less than 72 hr had passed between the onset of symptoms and the CT study. Patients with history of any other systemic illness or any known drug allergy were excluded from the present study. All the results were compiled in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Results: A total of 100 patients were assessment. Mean age of the patients was 53.8 years. Majority of the patients were males. According o CT grading, 61 percent of the patients were mild while the remaining were severe. Complications were seen in 18 percent of the patients. Mortality was present in 3 percent of the patients. Significant results were obtained while correlating CT grading with complications and mortality. Conclusion: CT scan is useful in early assessment of morbidity and mortality associated with acute pancreatitis.