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Volume 13 Issue 10 (October) 2024

Original Articles

Cytomorphological Features of Salivary Gland Lesions: Correlation with Histopathological Findings
Dr. Ankita Baghel, Dr. Monika Kushwaha, Dr. Archana Sagar, Dr. Priyanka Saxena

Aim: This study aims to evaluate the cytomorphological features of salivary gland lesions using fine-needle aspiration cytology (FNAC) and correlate these findings with histopathological diagnoses to determine the diagnostic accuracy of FNAC in identifying salivary gland tumors. Materials and Methods: A total of 80 patients with clinically suspected salivary gland masses were enrolled in this prospective observational study. FNAC was performed on all participants, followed by surgical excision of the lesion for histopathological examination. The cytological features were analyzed using standard stains, and the results were compared with histopathological findings to assess sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Data analysis was conducted using SPSS software version 26.0, with statistical significance set at a p-value of <0.05. Results: The study found that Pleomorphic Adenoma was the most common salivary gland lesion (37.50%), followed by Mucoepidermoid Carcinoma (22.50%) and Warthin's Tumor (15.00%). The correlation between cytological and histopathological findings showed a sensitivity of 89.50% and specificity of 92.30%. The PPV and NPV were 88.70% and 93.10%, respectively, with an overall diagnostic accuracy of 91.00%. Complications during the FNAC procedure were minimal, with 78.75% of patients experiencing no adverse effects. Conclusion: FNAC is a highly effective diagnostic tool for evaluating salivary gland lesions, with strong correlation to histopathological findings. While FNAC provides a reliable preoperative diagnosis, histopathological analysis remains essential in cases with complex or ambiguous cytological features to confirm the diagnosis and guide appropriate treatment strategies.

 
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