Thyroid cancer is the most frequently diagnosed type of endocrine cancer. Its incidence rate is rising more rapidly than that of any other cancer, affecting both men and women. Around 90% of thyroid cancers belong to the DTC category, with PTC being the most prevalent subtype, accounting for 75% of cases. The FTC subtype, on the other hand, comprises roughly 10% of all diagnosed thyroid cancers. The aim of this study is to analyze the cytomorphological features of various types of thyroid lesions and classify them according to The Bethesda System for Reporting Thyroid Cytology and to investigate the relationship between the thyroid hormone levels of patients and their cytomorphological characteristics. Our findings indicate that there is no significant correlation between the T3, T4, and TSH profile and cytological diagnosis of malignant thyroid lesions. Our study suggests that FNAC diagnosis and thyroid profile are independent variables.Another study, which involved 1500 participants, reported a noteworthy rise in the risk of malignancy among individuals with elevated TSH levels. The study found that malignant thyroid lesions had significantly higher TSH levels than benign ones. The likelihood of a thyroid lesion being malignant was 1.54 times higher in patients with elevated TSH levels. In some cases with abnormal T3, T4, and TSH levels, the thyroid hormone profile may be useful for symptom management.