Dental malocclusions rank as the third most prevalent oral pathology, following tooth decay and periodontal diseases, thus holding a significant position globally. The transmission of orthodontic forces through the strained tissue matrix to neighboring cells within the periodontal ligament and alveolar bone results in the release of pro-inflammatory, angiogenic, and osteogenic factors by these cells, thereby initiating the remodeling process of both the periodontal ligament and alveolar bone Orthodontic treatment, similar to other medical interventions, may entail certain adverse effects. It is crucial for both the orthodontist and the patient considering such treatment to be well-informed about these potential side effects.