Aim: This study aimed to determine the prevalence and risk factors of non-communicable diseases (NCDs) in urban slums, focusing on conditions such as hypertension, diabetes, obesity, and cardiovascular diseases. Material and Methods: A community-based cross-sectional study was conducted among 200 participants aged 18 years and above from urban slum areas. A structured questionnaire was used to collect data on socio-demographics, lifestyle factors, and medical history. Anthropometric measurements and blood pressure readings were recorded, and blood glucose levels were measured to assess diabetes prevalence. Data were analyzed using SPSS version 25.0, and logistic regression was applied to identify significant risk factors for NCDs. Results: Hypertension was prevalent in 30% of participants, diabetes in 25%, and obesity in 22.5%. The study identified key lifestyle risk factors, such as smoking (37.5%) and physical inactivity (55%). Hypertension and diabetes were strongly associated with age over 40 years, obesity, smoking, and physical inactivity. The risk of hypertension increased with obesity (OR: 3.0, p<0.01), while the risk of diabetes was significantly linked to age and family history of the disease (OR: 2.5, p<0.01). Conclusion: The study reveals a high prevalence of NCDs in urban slums, driven by modifiable risk factors such as unhealthy diets, physical inactivity, and smoking. Addressing these factors through targeted public health interventions is critical for reducing the NCD burden in vulnerable populations.