Background: Stroke is one of the leading causes of death, long-term disability, and hospital admission in the industrialized world. This study was conducted to evaluate the clinico-radiological profile of subjects having ischemic stroke Materials and Methods: This study presents a retrospective analysis of 100 cases of ischemic stroke. Participants were required to be over 18 years of age, and their symptoms and clinical signs had to align with the who's definition of stroke, confirmed by CT imaging indicating ischemic infarction. Statistical evaluations were performed using SPSS software. Results:This study involved 100 subjects (53 males, 47 females) with a majority aged 61-70 years (48%). Stroke characteristics included: right (36%) and left (52%) hemiplegia, with hypertension (26%) and diabetes mellitus (25%) being the primary risk factors. Cerebral infarction commonly occurred in the parietal (55%) and frontal (21%) regions. Conclusion: The occurrence of ischemic stroke was higher among individuals aged 61 to 70 years, exhibiting a greater prevalence in males. Hypertension emerged as the predominant risk factor.