Introduction: Several recent reports have indicated that Cp levels are elevated in patients with heart failure (HF), both in acute and chronic states and regardless of etiology. Furthermore, serum Cp levels appeared to be inversely correlated with LV ejection fraction but directly correlated with symptom severity especially in the non-ischemic group. Materials and Methods: 40 Individuals with abnormal lipid profile without any associated diseases like DM, HTN etc. Kinetic method amenable to automation for ceruloplasmin estimation with inexpension-50 μl sample + 1 ml reagent(1) → kept at room temperature for 1 min → 150 μl reagent(2) → measure in kinetic mode with factor 2012, lag time 10 secs. Lipid profile was assessed by standard methods. The data was analyzed by using Microsoft Excel. Results: However when correlations were seen separately for tests and controls, ceruloplasmin was positively correlated with LDL in dyslipidemics and with no other parameter of lipid profile (r = 0.434, p < 0.05) but not in control. Ceruloplasmin was negatively associated with TG in controls, but the correlation is not statistically significant. Conclusion: The present study showed that serum ceruloplasmin levels of dyslipidemics are significantly higher than normal healthy subjects. Thus raised ceruloplasmin can be considered as an added risk factor in dyslipidemic patients with regard to coronary artery disease.