Original Articles
An evaluation of FEV1, 6 Minute Walk Test and BMI as predictors of morbidity among cases of COPD Admitted in F.H. Medical College & Hospital Agra | |
Dr. Sanjeev Anand, Dr. Swati Bajpai, Dr. Rishi Yadav, Dr. Deepak Sikarwar | |
Introduction: Body mass index has an interesting relationship with COPD prevalence and severity. It also influences the lung function and exercise ability independently. Both COPD as well as Body mass index are independent predictors of morbidity. Objectives: To evaluate the usefulness of FEV1, 6-minute walk test and BMI as predictors of morbidity among cases of COPD Methods: A total of 100 COPD patients were enrolled (mean age 56.47 years; 74% males; mean BMI 20.86±5 kg/m²) and underwent BMI assessment, pulmonary function tests and 6minute walk tests. Assessment of severity of COPD was done using GOLD criteria. Number of exacerbations and hospitalizations during last one year were enquired. Correlation of 6minute walk test, BMI, FEV1, severity of COPD and its morbidity (in terms of exacerbation and hospitalization events) was done. Results: As per BMI, Maximum (40%) patients had normal weight followed by underweight (39%), overweight (18%) and obese (3%). Mean post- bronchodilator FEV1(% of predicted values) was 46.44±19.24% respectively. Maximum (n=36) cases were GOLD Grade D followed by Grade B (28%), Grade C (24%) and Grade A (12%). Mean actual distance covered was 286.34±85.69 meters (57.56±16.18% of the predicted value). With increasing severity grades of COPD there was a significant decline in mean BMI, post- bronchodilator FEV1 (% of predicted values) and distance covered on 6minute walk test. Underweight and obese patients as compared to normal and overweight BMI patients had significantly lower post-FEV1 values, shorter distance coverage on 6minute walk test and higher number of exacerbations and hospitalizations. 6minute walk test, FEV1 and BMI showed a significant mutual correlation as well as a correlation with COPD GOLD grade, number of exacerbations and number of hospitalizations Conclusion: BMI in normal and overweight range had a protective effect against COPD severity, better pulmonary functions (FEV1), exercise capacity and fewer exacerbation and hospitalization events. |
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