Background:Acute calculous cholecystitis is one of the most common clinical conditions frequently encountered in surgical department. Patients with acute calculous cholecystitis can be managed with either early laparoscopic cholecystectomy or initial conservative treatment followed by delayed laparoscopic cholecystectomy. It is still not clear which of these treatment modalities is preferable.Methods:The present study was designed to compare the outcomes of early laparoscopic cholecystectomy versus delayed laparoscopic cholecystectomy in patients with acute calculous cholecystitis.This comparative study was conducted in the Department of General Surgery, Adesh Medical College and Hospital, Shahbad. 50 patients were enrolled in the study and diagnosis of acute calculous cholecystitis was made by a combination of clinical, laboratory and radiological findings.IBM SPSS Statistics for Windows, Version 25.0. (Armonk, NY: IBM Corp.) was used for statistical analysis. Results were expressed as mean ± standard deviation. Results: The operating time and hospital stay was significantly shorter in the early group compared to delayed group.Conclusion:We recommend early laparoscopic surgery for acute calculous cholecystitis as it enables easier dissection, quicker access to Calot’s triangle, early symptom relief, shorter hospital stays and reduced financial burden.