Introduction: The liver plays a crucial role in thyroid hormone metabolism, converting T4 to active T3 and clearing plasma reverse T3. Thyroid hormones regulate liver cell metabolism and are essential for liver function. Hence, this study aimed to assess the relationship between thyroid function and liver disease severity in CLD patients. Materials and Method: This study was conducted among 71 adult patients with chronic liver disease (CLD) and cirrhosis. Participants underwent physical examination, laboratory tests, and ultrasound abdomen, and their data was analyzed using SPSS software. The relationship between thyroid function and liver disease severity using MELD and Child-Pugh scores was assessed. Results: The mean age of patients with chronic liver disease was 49.55 years, with 25.4% being elderly. Low FT3 levels were more common in patients with severe liver disease (Child Pugh score C), but the association was statistically insignificant. Similarly, no significant associations were found between thyroid hormone levels (FT3, FT4, TSH) and liver disease severity (Child Pugh score, MELD score). Conclusion: The present study found that thyroid abnormalities are common in patients with chronic liver disease (CLD), with free T3 levels being the most affected. Additionally, derangements in TSH and T4 levels were also observed in a significant proportion of patients. However, no significant association was found between the severity of liver disease and thyroid function tests. Further multicentric studies with larger sample sizes are needed to validate and support these findings.