Purpose: Digital eye strain comprises of visual and ocular symptoms which arises due to the prolonged use of digital electronic devices. The usual ocular symptoms presented by them are dry eyes, headache, foreign body sensation, itching, blurring of vision and watering. The study aimed to assess the prevalence of digital eye strain, the various risk factors of digital device usage pattern and to co-relate them statistically with clinical features. Place of study: Regional Institute of Ophthalmology, Guwahati Medical College & Hospital. Type of study: Hospital based Prospective cross-sectional study. Duration of study: 12 months. Materials and Methodology:500 participants were screened for Digital Eye Syndrome. All the patients were subjected to detailed history taking including pattern of device usage, visual acuity and slit lamp examination. Results: The age groups involved in the study were 11-30 (43.4%), 31-40 (34%) and above 40 (22.6%) years. Most symptoms show a significant increase in the >40 years age group, indicating that these symptoms are more prevalent among older individuals.In this study, 60 % were females and 40% were males indicating that age likely influences these symptoms. All the symptoms were statistically significant associated with average time spent for digital device usage, taking preferred break after 30 minutes of continuous usage of digital device, approximate distance of digital device from eyes except foreign body sensation and double vision. Conclusion: Dry eye, watering, headache, blurring of vision, and double vision show statistically significant differences in the prevalence between males and females. All the symptoms were statistically significant indicating digital eye strain. With increase in use of digital device, it has led to these asthenopic symptoms, hence public awareness should be implemented.