Blood pressure is the force exerted by circulating blood against the arterial walls. The elevation of the pressure is known as hypertension and is one of the major global health concerns. Early diagnosis and timely interventions are essential and in predicting prehypertension to include as regular panel marker, this current work correlated the biomarkers in normal, pre and stage-I hypertensives to set the risk ratio and cut-off values independently. The informed consent was obtained from all the age and gender matched participants from the respective groups i.e., control group, pre-hypertensive and hypertensive groups. The age group of 30 to 60 years were chosen for the study. All the individuals FBS, Fibrinogen, Malondiadehyde and High sensitive C-reactive protein (hSCRP). Among the parameters, fibrinogen, MDH and hsCRP, the serum hsCRP have showed slight elevation the pre hypertension group compared to control and can be treated as predictive marker provided by analysing the more sample size. The serum fibrinogen, MDH and hsCRP have shown an increase in the stage I hypertension group compared to control and pre HTN which are statistically significant. The biomarkers showed slight association in predicting the hypertension.