Aim: To assess the influence of intravascular contrast agent on apparent diffusion coefficient measures of ovarian neoplasms by the use of diffusion-weighted imaging. Materials and methods: This Prospective Study was conducted in the Department of Radiodiagnosis. 50 patients selected based on universal sampling, with Study population being women with newly diagnosed ovarian tumors who underwent CEMRI study to evaluate the nature of tumor and extent. Women referred from gynaec OPD for evaluation of ovarian neoplasms and With normal RFT were included in this study. Patients with Failed to follow up in our institute with HPE reports and Pregnant women were excluded from the study. Results: In benign ovarian tumors, Pre contrast mean ADC was 1.48± 0.46 and Post contrast mean ADC value was 1.40±0.62 with statistically insignificant P value. So it can be concluded that the contrast agent did not make much difference for measurement of ADC values in benign tumors. In malignant ovarian tumors, Pre contrast mean ADC was 0.91±0.20 and post contrast mean ADC value was 0.94±0.23 with statistically insignificant P value. So, it can be concluded that the contrast agent did not make much difference for measurement of ADC values in malignant tumors. ADC values of solid and cystic components in both benign and malignant tumors before and after administration of contrast, did not make statistically significant difference. Conclusion: ADC measures using our approach were not significantly changed after contrast administration for ovarian tumors at 1.5T. Our findings support the possibility that DWI optimized may be obtained before or after DCE-MRI without compromising important clinical information.Benign ovarian tumors had higher ADC values compared to malignant tumors, consistent with some of the previous studies.