Background: Medical education is long and stressful due to academic demands, frequent exams, excessive work load, chronic exposure to human suffering and death and vast extensive syllabus and increased psychological pressure due to multiple reasons, all of which can cause burnout. Aim: The aim of the study is to estimate the prevalence of academic burnout among undergraduate medical students of Rama Medical College, Kanpur and its correlation with year of medical education. Methods: A cross-sectional study was conducted by providing self-administered questionnaire containing socio-demographic datasheet and Burnout Self-Test Maslach Burnout Inventory. Descriptive statistics were used to analyse participants’ sociodemographic characteristics and prevalence of academic burnout using SPSS. The association of academic burnout with academic year was determined using the Pearson correlation coefficient. The data were also analysed using ANOVA. Results: Burnout among medical students was based on three dimensions: emotional exhaustion, depersonalization and decreased personal accomplishment. The results indicated that while most students maintained low levels of burnout in terms of depersonalization and personal accomplishment, i.e., 77.3% and 75.3% respectively, a notable percentage faced moderate (30.8%) to high (14.0%) levels of emotional exhaustion. As the academic year progressed, low-level burnout decreased, while moderate and high-level burnout increased significantly, with the fourth year having the highest rates of moderate and high-level burnout. Conclusion: High prevalence of burnout was found among undergraduate medical students. All the domains of burnout showed a clear progression as the academic year progressed.