Background:Visio-menstrual research and findings date well back into the 19th century. In 1887 Finkelstein a physician made some interesting observations and reported a concentric narrowing in the visual fields of healthy women during the pre-menstrual/ menstrual phases. The other sensory modalities of olfaction,auditory,taste, and touch generally show increased sensitivity and enhanced performance at midcycle with the opposite being evident in the premenstrual/menstrual phase. Aims and Objectives: To evaluate latency of visual evoked potential in healthy girls in different phases of menstruation. Material and Methods: The present study was conducted on 40 MBBS students(girls) in age group 18-25 years. V.E.P was performed in three different phases of menstrual cycle. Results: P100 latency(in milliseconds) in menstrual phases in left eye (77.4875) and right eye (76.5325)was significantly increased as compared to proliferative phase left eye(71.6200) and right eye(69.7245). P Value<0.01. The amplitude of N75 -P100 (in milliseconds) in secretory phase in right eye(mean=2.1542) and left eye(1.8022) was significantly higher as compared to proliferative phase in right eye ( mean=1.4017) and left eye(1.3388).P Value<0.05. Conclusion: Prolonged V.E.P latency in menstrual and secretory phase as compared to proliferative phase indicates high progesterone levels, may have an inhibitory effect on optic nerve conduction velocity.