Original Articles
Prolactin and its correlation with gestational age and birth weight in a new-born | |
Dr. Aditi Saini, Dr. Abhilasha Thakyal, Dr. Anumodan Gupta | |
Aim: To evaluate glycated hemoglobin levels and determine its relationship with pregnancy outcomes. Material and Methods: A total of 100 antenatal mothers, aged between 18 and 35 years, with a gestational period of more than or equal to 24 weeks, were included in the study. Antenatal mothers aged between 18 and 35 years and Gestational age of more than or equal to 24 weeks were included in this study. Demographic data, including age, were recorded for each participant. General, physical, and antenatal examinations were performed. Routine blood investigations and obstetric ultrasonography were also conducted as part of the initial assessment.Approximately five milliliters of blood was collected from each participant. The blood samples were analyzed for HbA1c levels using high-performance liquid chromatography (HPLC) on the same day as the oral glucose tolerance test (OGTT).The antenatal mothers were followed up until their delivery. Results: The HbA1c levels among the antenatal mothers were categorized into three groups: <5.7%, 5.7-6.4%, and >6.4%. Forty percent of the mothers had HbA1c levels below 5.7%, indicating normal glucose levels. The majority, 45%, had HbA1c levels in the prediabetic range (5.7-6.4%), while 15% had levels above 6.4%, suggesting potential gestational diabetes. The HbA1c levels with gestational age at delivery showed no significant differences. The mean HbA1c levels for gestational ages <37 weeks, 37-39 weeks, and >39 weeks were 5.3 ± 0.2%, 5.6 ± 0.3%, and 5.7 ± 0.3% for the <5.7% group; 5.9 ± 0.3%, 6.1 ± 0.2%, and 6.3 ± 0.3% for the 5.7-6.4% group; and 6.9 ± 0.4%, 7.1 ± 0.3%, and 7.3 ± 0.3% for the >6.4% group, respectively. The F-value was 1.76 with a p-value of 0.08, indicating no significant correlation between HbA1c levels and gestational age at delivery. Conclusion:Therewasnosignificantassociation between the maternal HbA1c levels in non- diabetic mothers and the adverse pregnancy outcome. |
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