Aim: To evaluate the hematological problems in individuals who have different orthopedic operations in a hospital setting. Material and methods: A total of 50 patients who were scheduled for elective and emergency orthopedic surgeries were enrolled in the study.Postoperative hematological evaluations were performed on postoperative days 1, 3, and 7. These evaluations included repeat CBC and coagulation profile tests to monitor changes in hematological parameters. Postoperative complications, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and bleeding, were recorded. All patients were monitored closely during their hospital stay and were followed up for 30 days post-surgery to assess any delayed hematological complications. Results: On postoperative day 1, the mean hemoglobin level decreased to 12.0 g/dL, reflecting blood loss during surgery. By day 7, hemoglobin levels had begun to recover, reaching 13.2 g/dL. WBC counts increased to 10.0 ×10^9/L on day 1, likely due to the surgical stress response, but decreased to 7.5 ×10^9/L by day 7. The postoperative outcomes show that the majority of patients had a hospital stay of less than 7 days (70%), while 30% stayed for 7 days or more. ICU admission was required for 10% of the patients, reflecting the severity or complications associated with their surgeries. Postoperative complications were observed in 20% of the patients, which included issues like infections and delayed recovery. The readmission rate within 30 days was 10%, indicating that a small proportion of patients experienced late-onset complications requiring further medical attention. The significant hematological complications observed post-surgery include deep vein thrombosis (DVT) in 6% of patients, pulmonary embolism (PE) in 4%, and prolonged bleeding in 10%. Conclusion: We concluded that while orthopedic surgeries are generally safe, it can lead to transient changes in liver function tests and hematological parameters. Monitoring these parameters closely in the immediate postoperative period is crucial to ensure patient safety and prompt management of any complications that may arise.