Background: The most significant human arboviral infection is dengue. The incidence of dengue fever (DF) and dengue hemorrhagic fever (DHF) has sharply grown during the past few decades on a global scale. The present study was conducted to assess hepatic manifestations in dengue fever and their correlation with severity of dengue fever. Materials & Methods:58 cases of dengue fever of both genders were assessed. Parameters such as hemoglobin, total and differential leukocyte count, hematocrit, platelet count, liver function tests and urine examinationwas assessed. Complete blood counts including hematocrit were repeated daily during the acute phase of the illness and chest X-ray was taken to demonstrate pleural effusion. Results: Out of 58 patients, males were 38 and females were 20. Common symptoms in patients with DF, DHF I, DHF II, DHF III and DHF IV was headache was seen in 7, 5, 10, 17 and 6 respectively. Body pain was seen in 6, 7, 6, 16 and 8, vomiting in 5, 3, 8, 12 and 3, retro-orbital pain in 8, 5, 7, 18 and 5 patients respectively. Jaundice in 7, 6, 6, 15 and 7 patients respectively. The difference was significant (P< 0.05). In DF, DHF I, DHF II, DHF III and DHF IV, the mean hemoglobin level was 10.3, 10.5, 11.2, 10.7 and 10.5. Haematocrit was 32.9, 31.5, 32., 32.0 and 32.5. Bilirubin was 0.62, 0.52, 0.63, 0.72 and 0.71 respectively. Conclusion: The frequency of dengue epidemics is rising. There have been reports of varied degrees of hepatic involvement. Early detection of hepatic dysfunction in dengue would help to prevent potentially fatal consequences because the condition is temporary and reversible.