Background: Heartburn and acid regurgitation (the typical symptoms of gastro-oesophageal reflux disease) are very frequent in Western countries. The present study was conducted to assess prevalence and risk factors of gastroesophageal reflux disease (GERD). Materials & Methods: 120 patients with complaint of heart burn of both genders were included. Lifestyle, and GERD for each subject was recorded.GERD was diagnosed by having 2 well defined GERD symptoms; heartburn which was defined as a burning feeling in epigastrium rises through the chest in substernal area and regurgitation which was defined if liquid coming back into the mouth leaving a bitter or sour taste. Results: Out of 120 patients, males were 70 and females were 50.GERD was present in 50 and absent in 60. 45 smokers had GERD, 40 NSAIDs/ Aspirin users had GERD, 35 non- fruit users had GERD and 38 beverages (Aerated) users had GERD. The difference was significant (P< 0.05). Conclusion: Most common risk factors for GERD was smoking, NSAIDs/ Aspirin, non- fruits users and beverages (Aerated) users.