Introduction- Dental implants are one of the common treatments involved for prosthetic rehabilitation of missing teeth. Hence; the present study was conducted for assessing CRP levels in implant failure patients. Materials and methods- 26 individuals diagnosed with implant failure based on clinical and radiographic criteria were recruited for the study. Another group of 26 participants attending routine health check-ups served as the healthy control group. Detailed clinical and demographic information was collected from all participants, and full-mouth periapical radiographs were taken as per established protocols. . Data analysis was performed using SPSS software. Results- 26 patients with implant failure and 26 healthy controls were done. In the study approximately 64% of the patients in the implant failuregroup and approximately 52% of the individuals in the control group were aged over 40 years.Furthermore, 61.5% of the implant failure patients and 46.1% of the control group participants were male. Conclusion-periodontal inflammation in patients with implant failureis often associated with a significant rise in CRP levels.