Background: Nitrates are highly effective both in terminating acute attacks of angina pectoris and for the prophylaxis of symptomatic and asymptomatic ischemic heart disease. The present study aimed to gather insights from Indian physicians and cardiologists regarding the occurrence of angina post-intervention and the treatment approach in a real-world setting. Methods: An observational survey-based study conducted by cardiologists and physicians with clinical expertise in the management of ischemic heart disease. A structured questionnaire was prepared to solicit the opinion of the experts regarding their practice and preference of drugs for the management of angina post-intervention in the real-world setting. Data entry and statistical analysis were done for completed questionnaires. Results: A total of 51 cardiologists participated in this survey. The majority of respondents (56.9%) reported that the occurrence of angina post-intervention [percutaneous coronary intervention or coronary artery bypass grafting] falls between 20-40%. A total of 41.1% of respondents preferred using a combination of beta-blockers and nitrates. In cases of microvascular angina, most cardiologists preferred a combination of beta-blockers and nitrates (33.3%), with nitrates alone (15.6%) and beta blockers alone (3.9%) being less favored. Conclusion: The present survey concluded that nitrates remain the favored choice of anti-angina medication in real-world clinical practice in India.