Background: Due to increased risk of uterine rupture with prostaglandins in previous cesarean patients, its use has been discouraged as ripening agent in previous cesarean patients. To compare efficacy ,safety and acceptability of intracervical foley’s catheter versus vaginal isosorbide mononitrate for induction of labor in women with previous one LSCS with an unfavourable cervix at term. Methods: A prospective clinical trial including 40 term pregnant women who were assigned randomly to receive either intracervical Foley catheter or moistened one tablet of IMN 40 mg vaginally was carried out. Induction to delivery interval and outcomes of labor, adverse effects and acceptability were assessed. Results: Four patients in foleys group and 5 patients in IMN group had prior vaginal delivery. Interpregnancy interval was more than 24 months in 75% of patients of both groups. IUFD was commonest indication for induction in both group followed by oligohydamnios. There was a significant improvement in the bishop score after 12 hr in both groups. Shorter induction to delivery interval was noted in the catheter group (22.2±4.99hr) compared to the IMN group (26.1±3.98 hr), with significant number of women delivered within 24hr in catheter group. There was significant number of patients who required oxytocin augmentation after AROM in IMN group (16 , 80%) in comparison to catheter group (10, 50%). Mode of delivery and rate of failed induction were not significantly different between two groups. Major maternal complication were not significantly different between two groups. There was a significant headache in IMN group (5,25%) in comparison to catheter group. There was significant maternal pyrexia in catheter group (6, 30%) when compared to IMN group. The neonatal outcome was not significantly different between two groups. Conclusion: Intracervical Foley catheter is effective, safe and acceptable for labor induction in women with previous one lower segment caesarean section at term when compared to vaginal IMN but, with more maternal pyrexia.