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Volume 3 Issue 2 (April-June) 2014

Original Articles

Assessment of papillary thyroid carcinoma- A histopathological study
Dr. Neetu Verma

Background: The notion that there is a familial form of thyroid cancer has gained widespread acceptance due to early reports of well-differentiated non-medullary thyroid carcinoma clustering in families and studies using population and hospital data bases showing that such cases occurred in families more often than could be explained by chance. The present study evaluated histopathological features of papillary thyroid carcinoma. Materials & Methods: 80 thyroid tissues were classified into histological pattern into three groups: classic papillary, follicular, or solid. PTCs were subdivided into main histological variants as classic papillary, follicular, solid, diffuse-sclerosing, Warthin-like or mixed. Results: Out of 80 specimens, 38 were of males and 42 were of females. Histopathological variant was papillary in 16, follicular in 32, solid in 8, diffuse-sclerosing in 14 and warthin like in 10 patients. 28 had capsules and 52 had not. Tumor size was 1-10 mm in 30 and 11-50 mm in 50 cases. Pattern was papillary in 21, follicular in 35 and solid in 24 cases. The difference was significant (P< 0.05). Conclusion: Follicular pattern was observed in maximum specimens. In most of the cases, 11-50 mm size was observed.

 
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