Background: Pregnancy and liver illness are not commonly associated. Pregnancy and liver illness can have dangerous outcomes. Its incidence and impact on pregnancy outcomes have not been thoroughly studied till now. Aim and objectives: The present prospective observational study was conducted to assess effect of liver disease on maternal and foetal outcome. Materials & Methods: 65 women with pre-existing liver disease or those suspected to have liver dysfunction were enrolled. Maternal and perinatal outcome were recorded. Results: Liver diseases in pregnancy found to be cholestatic jaundice in 28, viral hepatitis in 20 and HELLP syndrome in 17 women. The difference was non- significant (P> 0.05). The study shows that the age in years (mean±SD) found to be 30.79 ± 5.01 in cholestatic jaundice, 31.38±4.13 in viral hepatitis and 31.57±3.94 in HELLP syndrome. The statical difference was non- significant (P> 0.05). It also shows that in primigravida, cholestatic jaundice was found in 11, viral hepatitis in 8 and HELLP syndrome in 10. In multigravida cholestatic jaundice was found in 17, viral hepatitis in 12 and HELLP syndrome in 7 patients. The statical difference was non- significant (P> 0.05). The liver diseases in pregnancy found to be cholestatic jaundice in 28, viral hepatitis in 20 and HELLP syndrome in 17 women. The mode of delivery in cholestatic jaundice, viral hepatitis and HELLP syndrome women was normal vaginal in 16, 10 and 8. It was forceps delivery in 7, 6 and 4 and caesarean delivery in 5, 5 and 4 women. Maternal complications were abortion in 2, 1 and 2, PROM in 1, 0 and 2, preterm labour in 1, 2 and 1, IUGR in 3, 1 and 1, meconium staining in 1, 0 and 3, PPH in 0, 1 and 2, ARF in 1, 0 and 1, DIC in 0, 2 and 1 and maternal deaths was 2, 1 and 0 respectively. Perinatal outcome was neonatal hypoglycemia in 3, 1 and 2, neonatal hepatitis in 1, 4 and 3 cases and neonatal death in 1, 2 and 1 case. The difference was non- significant (P> 0.05). Conclusion: Even in a tertiary referral center, liver disease is linked to maternal and perinatal mortality, although being rare in our study. In order to enhance maternal and perinatal outcomes in pregnant women with liver illness, early diagnosis, proper supportive care, and a proactive policy of early delivery are therefore necessary.