Aim: The aim of the present study is to compare the efficacy and safety of sub-tenon block to peribulbar block with respect to analgesia, akinesia, and complications.Methods: Patients who came to the outpatient department for cataract surgery were included in the study. A written, informed consent was taken from all patients before their participation in the study. Patients were randomized into two groups of 50 each.Results: The baseline and postoperative pain scores were significantly greater in the peribulbar group P < 0.001. The time of onset of akinesia in both the groups showed a significant difference, with a mean time of 196.44 s in peribulbar and 92.38 s in the sub‑tenons group P < 0.001. The presence of chemosis and subconjunctival hemorrhage showed no statistically significant difference in both groups. We noted that only 6% in the peribulbar group and 20% in the sub‑tenons group had chemosis. None of the patients in the peribulbar group had a subconjunctival hemorrhage, whereas 10% in the sub‑tenons group had subconjunctival hemorrhage.Conclusion: Sub‑Tenon block is an effective and safer technique of ocular anesthesia for SICS. It can be considered as an alternative to the conventional peribulbar block.