Fucoxanthin, a natural carotenoid primarily found in brown seaweed, has garnered significant attention in recent years due to its potential anti-cancer properties. Research exploring its effects on various types of cancer, including ovarian cancer, has shown promising results in inhibiting tumor growth, inducing apoptosis, and suppressing the spread of cancer cells.Ovarian cancer is one of the most lethal gynecologic malignancies worldwide. Its high mortality rate is often attributed to late diagnosis, limited treatment options, and the development of drug resistance. Therefore, the quest for novel and effective therapeutic agents to combat ovarian cancer remains a crucial area of research. Fucoxanthin, with its unique biological properties, has emerged as a potential candidate in this pursuit. Fucoxanthin has been shown to induce apoptosis in ovarian cancer cells. This programmed cell death mechanism is crucial in eliminating damaged or abnormal cells. Fucoxanthin triggers apoptotic pathways within cancer cells, leading to their self-destruction, thereby impeding tumor growth and metastasis. Considering pieces of evidence of the anticancer effects of Fx on various cancers, we investigated the anticancer properties of this carotenoid on ovarian cancer cells (PA-1) compared to the standard anticancer drug tamoxifen (Tx).