Aim: To examine the range of histopathological characteristics seen in central nervous system tumors. Materials and Methods: The present retrospective study is conducted in department of pathology. In the present study a total of 50 cases of CNS tumors were diagnosed and categorized according to the WHO 2016 classification while immunohistochemistry done wherever required. CNS tumors of all age groups were included while cases with incomplete data were excluded from study. According to the WHO 2016 classification of CNS tumors molecular parameters were included along with histolopathological examination. Results: In our study CNS tumors were most frequently seen in cerebrum comprising of 31 cases (62%) out of which frontal lobe of cerebrum were the most common site followed by parietal and temporal lobe respectively. All CNS tumors were histopathologically categorized according to the WHO 2016 classification system and were graded from I-IV. In our study out of total 50 CNS tumors, WHO grade I tumor was considerably higher comprising 26 cases (52%), WHO grade II tumor was 11 cases (22%), WHO grade III tumor was 5 cases (10%) and WHO grade IV tumor was 8 cases (16%). Most common histopathological subtype was Meningioma (25) followed by Astrocytic(12), Oligo dendroglial(4), Ependymal(4), with one case each of Astroblastoma, Ganglioglioma, Hemangioblastoma and Atypical choroid plexus papilloma. Overall tumor of meninges (50%) was the most common with female predominance. The median age of meningioma was 43.35±5.36 years. The most common histological subtype was transitional meningioma followed by fibroblastic and meningiothelial meningioma with one case of Anaplastic meningioma. Conclusion: The present study reflects the histopathological spectrum and incidence of various types of CNS tumors in both adults as well as pediatric age groups. Rising global trends in the incidence of CNS tumors have been observed despite of age. Irrespective of advanced imaging techniques, the histopathological examination continue to exist as gold standard in their diagnosis and classifying CNS tumors.