Aim: To investigate the morphological pattern of anaemia. Materials and Methods: A hospital based prospective observational study was carried out at Department of Pathology. 100 patients were evaluated for morphological pattern of anaemia based on red cell indices, peripheral smear, and leukocyte and platelet parameters. Anaemia was defined according to WHO criteria as haemoglobin concentration lower than 13 g/dL in men and 12 g/dL in women. Informed consent was obtained from patients. Results: The results of complete blood count (CBC) and peripheral blood picture (PBP) showed that 30 (30%), 56 (56%), and 14 (14%) of thepatients had normocytic normochromic, microcytic hypochromic and macrocytic pattern of anaemia respectively. The gender wise classification of the patterns revealed that 14 male patients and 16 female patients had normocytic normochromic patterns, while 46 female patients and 10 male patients had microcytic hypochromic patterns whereas 6 males patients and 8 case of female patients showed macrocytic pattern. Other significant findings seen in this study among patients of anaemia are: pancytopenia 13 (13%), neutrophilia 11 (11%), PMN toxic granules 4 (4%), eosinophilia 2 (2%), lymphocytosis 11 (11%), and immature cells 4 (4%). Conclusion: Morphological patterns of anaemia reflect the underlying aetiology, the study of which would ensure benefits in the early detection and appropriate treatment.